It’s no wonder that Route 66 is regarded as a true American icon and a legendary road. Americans call it “The Mother Road” because it was one of the nation’s first federal highways, stretching across a huge portion of the country. The allure and spirit of adventure of this road make traveling it absolutely unforgettable.
- Travel Itinerary
- Day 1: Departure from Your City – Chicago
- Day 2: Explore Chicago
- Day 3: Chicago to St. Louis
- Day 4: St. Louis to Springfield
- Day 5: Springfield to Oklahoma City
- Day 6: Oklahoma City – El Reno – Weatherford – Clinton – Elk City – Amarillo
- Day 7: Amarillo to Tucumcari
- Day 8: Tucumcari to Albuquerque
- Day 9: Albuquerque to Holbrook
- Day 10: Holbrook to Grand Canyon
- Day 11: Grand Canyon to Las Vegas
- Day 12: Las Vegas to Los Angeles
- Day 13: Explore Los Angeles
- Day 14: Return Home
- Day 15: Arrival at Home
- Price
- What’s Included
- What’s Not Included
- Departures
- Duration
- Route Map
- Why Your Amazing Fly & Drive Begins Here
- Fly & Drive Specialists
- Travel at Your Own Pace
- Save Time
- Great Deals & Flexible Payments
- Traveler Reviews
- Travel Conditions
Along the way, you’ll meet other travelers following the same path and locals striving to preserve the original Route 66 spirit through their businesses or simply by sharing tales. Don’t hesitate to ask them for the best-kept secrets of “The Main Street of America”, another name by which it’s known.
This adventure offers you plenty of freedom—you can stop wherever you like, even in small towns that might not appear on any map. Plus, you won’t need to worry about getting lost: Route 66 is well signed and runs parallel to a major highway, so if you linger too long at a stop, you can always make up for lost time.
During your trip, you’ll also get to visit two major cities—Chicago and Las Vegas—as well as spend a night near the breathtaking Grand Canyon. To complete this unforgettable journey, enjoy a stay in Los Angeles, the most cosmopolitan city on the West Coast. Ready to take it all in?
Day 1: Departure from Your City – Chicago
Your adventure kicks off with a flight from Italy to the “Windy City” of Chicago. After your long flight, you’ll land at Chicago O’Hare International Airport, one of the world’s busiest hubs. Once there, make your way to your hotel and rest up for what’s to come.
Day 2: Explore Chicago
Dedicate your day to discovering the treasures of Chicago. The city is famous for its distinctive architecture, world-class museums, charming parks, and vibrant cultural scene. Visit Millennium Park, check out “The Bean” sculpture, and stroll along Lake Michigan’s shoreline. Don’t miss the classic deep-dish pizza, a true Chicago specialty.
Day 3: Chicago to St. Louis
It’s time to leave Chicago and hit the legendary Route 66. Your first stop is St. Louis in Missouri. On your way, marvel at the changing landscapes as you pass through Illinois and Missouri. In St. Louis, visit the iconic Gateway Arch, symbolizing the gateway to the American West.
Day 4: St. Louis to Springfield
Continue to Springfield, the capital of Illinois. Along the way, soak in the impressive Midwest scenery and the rich Route 66 history and culture. Once in Springfield, visit the Abraham Lincoln Presidential Library and Museum, dedicated to America’s beloved president.
Day 5: Springfield to Oklahoma City
Today you’ll cross Oklahoma, one of Route 66’s most fascinating states. Admire spectacular landscapes and stop in towns like Catoosa, famous for its iconic Blue Whale statue. On arrival in Oklahoma City, dive into cowboy culture and explore the state’s unique history.
Day 6: Oklahoma City – El Reno – Weatherford – Clinton – Elk City – Amarillo
Travel further west through Oklahoma to Amarillo, Texas. Enjoy vast Texan plains and visit towns like Elk City and Clinton. Amarillo is known for the Big Texan Steak Ranch, where you can test your appetite for giant steaks. You’ll be crossing the authentic heartland of America—it’s likely to be one of your favorite days on Route 66. Before leaving town, enjoy breakfast with one of their delicious local fried pastries—perfect to take away for a picnic stop by Lake Overholser Bridge, a spot of lawns, a lake, and a picturesque bridge.
Day 7: Amarillo to Tucumcari
Today, cross from Texas into New Mexico and reach Tucumcari. Along the way, you’ll experience desert landscapes and discover small retro towns along Route 66. Tucumcari is famed for its neon signs—giving you a real sense of time travel. Today you’ll also reach the midway point of your trip. Hit the road with energy, as several unique sights await you, starting with Cadillac Ranch, where you can add your mark by painting one of twelve half-buried Cadillacs.
Day 8: Tucumcari to Albuquerque
Continue across New Mexico to Albuquerque, one of Route 66’s most fascinating cities. Immerse yourself in local culture and explore the historic Old Town, full of art, crafts, and traditional cuisine.
Day 9: Albuquerque to Holbrook
Consider visiting Petrified Forest National Park, famous for its fossilized trees turned to stone over the ages. After this unique stop, continue to Holbrook in northern Arizona.
Day 10: Holbrook to Grand Canyon
Your Route 66 adventure leads you to the Grand Canyon, a world-renowned natural wonder. Spend a full day exploring the stunning scenery—enjoy hiking, panoramic viewpoints, and capture unforgettable photos.

Day 11: Grand Canyon to Las Vegas
Leave the Grand Canyon and head for Las Vegas, America’s ultimate entertainment capital. Renowned for its casinos, glitzy shows, and vibrant atmosphere, Las Vegas promises a night of luxury and excitement. Stay at one of the famous hotels and perhaps try your luck at the tables.

Day 12: Las Vegas to Los Angeles
It’s time to say goodbye to Las Vegas and travel to your final destination: Los Angeles. Drive through the Mojave Desert and enjoy inspiring views. Once in LA, explore the city’s lively pace, visit iconic sites like Hollywood, Beverly Hills, and Santa Monica, and dive into California’s culture and cuisine.
Day 13: Explore Los Angeles
Spend the day discovering LA at your own pace—whether touring museums, shopping on Rodeo Drive and Melrose Avenue, relaxing on the beaches of Santa Monica and Venice Beach, or tasting new dishes at local restaurants, LA offers endless options.

Day 14: Return Home
It’s time to bid farewell to Route 66 and Los Angeles. Catch your flight back home with unforgettable memories of this great journey along “The Main Street of America.”
Day 15: Arrival at Home
You return home with your mind full of emotions and souvenirs from your incredible adventure on Route 66. As you look through your photos, you’ll relive those unique experiences on this legendary road.
Price
What’s Included
- Round-trip flights.
- Stay in selected hotel in Chicago.
- Meal plan of choice in Chicago.
- Stay in selected hotel in Saint Louis.
- Meal plan of choice in Saint Louis.
- Stay in selected hotel in Springfield.
- Meal plan of choice in Springfield.
- Stay in selected hotel in Oklahoma City.
- Meal plan of choice in Oklahoma City.
- Stay in selected hotel in Amarillo.
- Meal plan of choice in Amarillo.
- Stay in selected hotel in Tucumcari.
- Meal plan of choice in Tucumcari.
- Stay in selected hotel in Albuquerque.
- Meal plan of choice in Albuquerque.
- Stay in selected hotel in Holbrook.
- Meal plan of choice in Holbrook.
- Stay in selected hotel in Grand Canyon -Az.
- Meal plan of choice in Grand Canyon -Az.
- Stay in selected hotel in Las Vegas.
- Meal plan of choice in Las Vegas.
- Stay in selected hotel in Los Angeles.
- Meal plan of choice in Los Angeles.
- Car rental.
- Travel insurance.
- Fee for pick-up and drop-off of the vehicle in a different location.
What’s Not Included
- Electronic authorization (ESTA/ETA) for US entry
- Resort fees in the United States
- Possible highway tolls
Departures
Milan, Bologna, Venice, Rome, Bari
Duration
15 days.
Route Map

Why Your Amazing Fly & Drive Begins Here
There are many reasons to start your epic Route 66 road trip with FullTravel.it’s partner.
Fly & Drive Specialists
Our partner is an expert in fly & drive trips. All our itineraries are perfectly planned to help you discover top destinations worry-free. With us, you travel at your own pace for a truly unique experience.
Travel at Your Own Pace
Our fly & drive packages include flights, hotels, itineraries, car rental and travel insurance. Travel independently, deciding where and when to stop along Route 66. No stress, no rigid itinerary.
Save Time
With FullTravel.it’s partner you get real-time availability and instant booking, planning your trip quickly and easily. Our partner is always available—for assistance 24/7.
Great Deals & Flexible Payments
Find your perfect fly & drive at the best price thanks to exclusive offers. Plus, take advantage of the option to pay in easy, interest-free installments to make your journey even more affordable.
Traveler Reviews
We’ve collected testimonials from those who’ve already traveled Route 66 with us. Here’s what they say:
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“This trip was absolutely incredible! We discovered unique places and met amazing people along the way. Thank you for making everything so simple and well organized!” – Marco, Milan
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“Route 66 is a true dream come true. Every leg of the journey was exciting and we created unforgettable memories all along the way. Highly recommended!” – Laura, Rome
Travel Conditions
Before setting off on your Route 66 adventure, keep these important conditions in mind:
- Travel insurance included. Your booking covers luggage, missed connections, repatriation, and medical expenses up to €1,500 abroad. Coverage for trip cancellation due to terrorism and/or natural disasters up to €3,000 is also included.
- Easy payment option. Our partner lets you pay in convenient interest-free installments for bookings made at least 30 days in advance, giving you more flexibility when planning.
- Important notes. Tipping is customary in the US. Some cities may charge a resort fee, payable locally. Don’t forget to check for highway tolls and whether any specific authorizations are required to drive through certain regions or states.
Gear up for the adventure of a lifetime on legendary Route 66. Book your trip with FullTravel.it’s partner and get ready for unforgettable memories along “The Main Street of America.”
This trip is organized by LogiTravel. FullTravel is an affiliate partner.

